SCIENTIFIC AND TECHNOLOGICAL CENTERS IN CNIC

The establishment of scientific and technological centers in CNIC was based on the analysis of the focus and the success of the existing and currently implemented strategic projects at all involved universities and institutes of SAS (see above), with an emphasis on the application potential of particular projects. The centers represent the “startup structure” of CNIC and are placed in a distributed structure the “Points” which are separate pavilions of the CNIC.

  • CENTER FOR INTERDISCIPLINARY BIOSCIENCES (CIB)
  • CENTER FOR PROGRESSIVE MATERIALS (CPM)
  • CENTER FOR TRANSLATIONAL MEDICINE (CTM)
  • CENTER FOR BIOMEDICAL ENGINEERING (CBE)
  • CENTER FOR GREEN AND DIGITAL TECHNOLOGIES (CGDT)
  • CENTER FOR HYDROGEN TECHNOLOGIES (CHT)
  • CENTER FOR QUANTUM AND INFORMATION TECHNOLOGIES (CQIT)
  • FUTURE MATERIAL AND BIOMEDICAL TECHNOLOGIES

    CIB is an interdisciplinary science and technology center whose activity focuses on the intersection between biology, chemistry, physics, mathematics and informatics, and on the transfer of scientific knowledge into practice. The major mission of the CIB is to conduct high-quality basic research in the fields of protein engineering, nanomedicine, bioenergetics and the environment. This is followed by the development of new technologies and innovations for the diagnosis and treatment of serious diseases as well as for environmental analysis, and their marketing and the application of the latest scientific findings in economic practice and education.

    FOCUS OF RESEARCH & APPLICATION:

    1. Nanomedicine
      1. Development of selective nanotransport systems for targeted delivery of antitumoral/antimicrobial/antiviral drugs
      2. Photodynamic therapy (PDT)
    2. Protein engineering – research and development of proteins with biotechnological and pharmaceutical significance
      1. Development of proteins/enzymes with significance for biotechnological (e.g. dehalogenases) and pharmaceutical (e.g. thrombolytics) applications
      2. Development of peptides to block the interaction between host cell receptors and viral antigen
    3. Aging
      1. Aging and oxidative stress
      2. Aging and protein misfolding diseases
    4. Advanced technologies for environment analysis and protection
      1. Development of reliable and sensitive methods for detecting very low drug concentrations in the biological environment, as well as environmental pollutants in water and food and optimization of the nanochip for the detection of low concentrations of organochloride pesticides in water and food.

    INTERNATIONAL COOPERATION OF CIB:

    The driving ambition of the CIB team is to confirm the quality of science in the abovementioned research fields by gaining prestigious international grants (in the near future especially under the Horizon Europe programs). This ambition is supported by real cooperation and joint projects of the CIB teams with prestigious foreign counterparts, such as University of Zürich (Switzerland), EPFL Lausanne (Switzerland), Technical University in Munich (Germany), IEM CSIC Madrid (Spain), Pierre and Marie Curie University (Paris, France), Masaryk University (Brno, Czech Republic), CEITEC Brno (Czech Republic), Charles University (Prague, Czech Republic). This network of international cooperation forms an exceptionally strong base for the increase in the quality of basic research and further application of the obtained results in the high-tech industry.

    MEMBERSHIP IN INTERNATIONAL NETWORKS:

    The European Research Infrastructure for Imaging – Euro-BioImaging (EUBI)
    www.eurobioimaging.eu offers individual users open access to a wide range of modern technologies in biology and medicine imaging. EuBI consists of 29 geographically distributed “nodes” (specialized imaging laboratories) that offer grants for their use to scientists from all over the world. Currently, scientists can apply for experiments on 36 original technologies (CIB as one of the EuBI nodes offers its own unique laboratory for optical microscopy).

    KEY PERSONALITIES:

    Pavol Miškovský, prof. RNDr., DrSc., Erik Sedlák, doc. RNDr., DrSc., Daniel Jancura, doc. Mgr., PhD., Gabriel Žoldák, doc. RNDr., PhD., Andrey Musatov, MUDr., DrSc.
    Mangesh Bhide, doc. MVDr., PhD., Juraj Pistl, prof. DVM., PhD., Dáša Čížková, doc. MVDr., DrSc.

    FUTURE MATERIAL AND BIOMEDICAL TECHNOLOGIES

    CPM focuses on research, development, and application of new progressive materials with exceptional physical, chemical, biological and mechanical properties as well as research and development of technologies and testing methods for their production and characterization. The aim is to transfer knowledge from basic research in the field of physics, chemistry, and material research into final applications in the field of sensors, actuators, computer memories, and modern spintronic devices.

    FOCUS OF RESEARCH & APPLICATION:

    1. Multifunctional materials with outstanding physical properties (structural and multifunctional materials)
    2. Power and energy materials
    3. Nanomaterials for biomedical and technical applications
    4. High entropy ceramics/alloys for future application

    INTERNATIONAL COOPERATION OF CPM:

    In the framework of the research on modern progressive materials, CPM cooperates with major scientific departments such as ICMM CSIC Madrid, UPV San Sebastian, University of Oviedo, University of Paris-Sud, University of South Florida, Tampa, University of Latvia, University Bordeaux, Lund University, Queen Mary University of London, Aix-Marseille University, Charles University, Prague, MoU: Fiber Consultoria em Tecnologia Ltd, Brasil, Institute of Transport and Systems and Technologies, Ukraine and with national academy institutes in Czech Republic, Ukraine, India, etc. In our research, we perform experiments in large European facilities, eg. DESY, Hamburg, Germany, ILL, Grenoble, France and Diamond Light Source, UK. Distribution.

    KEY PERSONALITIES:

    Rastislav Varga, prof. RNDr., DrSc., Ján Dusza, prof. RNDr., DrSc., Pavol Hvizdoš, doc. RNDr., DrSc., František Lofaj, doc. RNDr., DrSc., Karel Saksl, Ing., DrSc., Peter Baláž, Dr.h.c. prof. RNDr. DrSc., Peter Kollár, prof. RNDr., DrSc.

    FUTURE MATERIAL AND BIOMEDICAL TECHNOLOGIES

    CTM conducts coordinated medical research especially in the areas of personalized and regenerative medicine. Its goal is the continuous creation of effective diagnostic and treatment modalities in the specified areas and providing effective guidance to the population on changing unhealthy habits and lifestyle with the aim of long-term reduction of morbidity.

    FOCUS OF RESEARCH & APPLICATION:

    1. Regenerative medicine
      1. Pancreatic islet transplant program
    2. Sports medicine and healthy aging
    3. Smart rehabilitation, prosthetics and orthotics
      1. SmartZone – Personalized services for vulnerable persons and persons with special needs
      2. RehabZone
    4. Personalized medicine
      1. Personalized diagnostics
      2. Personalized therapy

    INTERNATIONAL COOPERATION OF CTM:

    CTM has developed wide international cooperation on specific themes related to particular programs. In the case of encapsulation of pancreatic islets, it is especially the JDRF Encapsulation Consortium, which brings together about 50 research centers, universities and companies from around the world. Within the current JDRF-funded project, CETCM collaborates with CellTrans, Inc. (co-PI J. Oberholzer), NTNU Trondheim (co-PI A.M. Rokstad) and the Institute of Macromolecular Chemistry of the Academy of Sciences of the Czech Republic (V. Raus). In the field of personalized medicine, we rely on collaboration with teams of the following international institutions: the National Cancer Institute, USA, the National Institute on Aging, USA, the National Institute of Arthritis and Musculoskeletal and Skin Diseases, USA, Rockefeller University, USA, University of Iceland, Iceland, University of Southern Denmark, Denmark, Hadassah Medical Center, and the Hebrew University of Jerusalem, Israel.

    MEMBERSHIP IN INTERNATIONAL NETWORKS:

    European Clinical Research Infrastructure Network – ECRIN http://www.ecrin.org/ is a public non-profit organization that brings together research partners and networks in Europe to increase the effectiveness of transnational clinical research through the management and support of cross-border clinical trials, networking and consulting. The implementation of ECRIN policy enhances the flow of knowledge, competitiveness and integration in European clinical research. CETCM is the ECRIN’s coordination unit in Slovakia.

    KEY PERSONALITIES:

    Pavol Jarčuška, prof., MUDr., PhD., Daniel Pella, prof., MUDr., PhD., Martin Pupiš, doc. PaedDr., PhD., Alena Buková, Mgr., PhD., Ján Junger, prof. PaedDr., CSc., Igor Lacík, Ing.,

    FUTURE MATERIAL AND BIOMEDICAL TECHNOLOGIES

    CBE conducts interdisciplinary research, especially in the areas of medical additive and bio-additive manufacturing, personalized implantology, digital surgery, regenerative medicine and rehabilitation. Its goal is to use digital software, augmented and virtual reality tools for precise aimed pre-surgery diagnostics, surgery preparation and guiding and additive production technologies for research and development of personalized medical devices for diagnostics and therapy. CBE will closely cooperate with CTM within personalized and regenerative medicine and with the Access Centre at TUKE that serves for the support of students with special needs and develops new services based on advanced ICT and Assistive technology applying users centered approach creating better conditions for an inclusive environment with personalized technology and services.

    FOCUS OF RESEARCH & APPLICATION:

    1. Research and innovation in anti-virus and anti-bacterial protective aids and devices
      1. BiZone Digital – AR, VR and CAD/CAM tools for digital surgery planning and guiding and personalized medical devices design
      2. BiZone – Technology – Personalized additive and bioadditive manufacturing, and special technologies for minimally invasive surgery
    2. ProtectiveZone – Research and innovation in anti-virus and anti-bacterial protective aids and devices

    INTERNATIONAL COOPERATION OF CBE:

    CBE has developed wide international cooperation on specific themes related to medical additive manufacturing, rehabilitation treatment, related diagnostics and prevention. In the field of personalized medicine, we rely on collaboration with teams of the following international institutions: Illinois University in Chicago (USA) YSU Ohio (USA), the University in Ghent, Belgium, the University of Padova (Italy), Politecnico di Milano (Italy), J. Kepler University in Linz (Austria), Laboratory for Rehabilitation and Motor Control of Walking, Faculty of Health Sciences, Ben-Gurion University (Israel), AAATE – Association for the Advancement of the Assistive Technology in Europe, and EASTIN consortium and several companies, e.g. Materialise (Belgium), Lithoz (Austria).

    MEMBERSHIP IN INTERNATIONAL NETWORKS:

    Rehabilitation International (RI), International Commission on Technology and Accessibility (ICTA) Subcommission of Rehabilitation International; International Measurement Confederation IMEKO TC17 – Measurement in Robotics; AAATE – Association for the Advancement of Assistive Technology in Europe, member of Scientific committee Int. Journal Technology&Disability; EASTIN – national contact for EASTIN global database; International Society for Gerontechnology – ISG, member of Scientific committee Int. Journal Gerontechnology since 2013, International Society for the Measurement of Physical Behavior (ISMPB), European Cooperation in Science and Technology (COST), expert evaluator since 2015

    Kľúčové osobnosti:

    Jozef Živčák, mult. Dr.h.c. prof., Ing., PhD., Radovan Hudák, prof. Ing., PhD., Dušan Šimšík, prof. Ing., PhD., Sergej Hloch, prof. Ing., PhD., Marek Bundzel, doc. Ing., PhD.

    GREEN TECHNOLOGIES

    CGDT transforms smart ideas and knowledge from laboratories into applications with the aim to support and innovate industry. The key emphasis is placed on clean and smart materials, technologies, approaches reflecting on environmental aspects together ensuring the quality of health in public life. Research at CGDT will contribute to ambition for zero emission mobility, zero waste environment in smart cities and regions. One of the main challenges facing humanity in this century is the reduction of greenhouse gases and climate change through application of clean and smart technologies. Another important topic is a sustainability of processes mainly focusing on transformation of the energy sector, energy safety and security and in general decarbonization of industry. Strategy of CGDT relates to the action plans of the European Commission, government and regions on fulfilling climate ambitions hand in hand with technological evolution.

    FOCUS OF RESEARCH & APPLICATION:

    1. Batteries and energy storage
    2. Recycling
    3. Safety of materials and technologies
    4. Materials and sensors for sport
    5. Digitalisation in material science

    INTERNATIONAL COOPERATION OF CGDT:

    The CGDT ‘s collaborating partners in the field of scientific research include institutions and companies such as TU Wien (Austria), IST Lisboa (Portugal), University of Ljubljana (Slovenia), KTH Stockholm (Sweden), ČVUT Prague (Czech Republic), VUT Brno (Czech Republic), University J.D. Czestochowa (Poland), KIT (Germany), Fraunhofer ISC (Germany), Western University (Canada). Memorandum of Understanding for cooperation in research and education in the field of green technologies with Coventry University (Great Britain), Memorandum of Understanding with European Battery Academy, InnoEnergy (EBA) and others. On the national level, CGDT is cooperating with University Spartacus on the topic of sensors.
    Other CGDT members established collaboration with institutes such as ICN2 Barcelona, USUCHT Dnepropetrovsk, WWU Münster, Charles University Bratislava, University of Žilina, Brno University of Technology, University of Chemistry and Technology Prague, University of Tomáš Baťa Zlín, and companies like Fecupral, Inobat, Theion, T-Systems, ZŤS VaV, Greenway Bratislava and others. Several years of cooperation with Brno University of Technology resulted in two EU patents in the field of Li-S batteries.

    MEMBERSHIP IN INTERNATIONAL NETWORKS:

    CGDT team members have already established cooperation with European Defence Agency (EDA Captech), NATO Science for Peace and Security Program, are members of working groups at BEPA – Batteries Europe Partnership, Clean Hydrogen Joint Undertaking, Hydrogen Europe, American Chemical Society, International Association of Advanced Materials, Council for Just Transition Fund and others.

    KEY PERSONALITIES:

    Maroš Halama, Assoc. prof., M.Sc., PhD., Renáta Oriňáková, prof., RNDr., DrSc., Andrea Fedorková, Assoc. prof., RNDr., PhD., Jozef Janovec, prof., Ing., DrSc., Karel Saksl, Assoc. prof., Ing., DrSc., Jana Shepa, RNDr., PhD., František Ďurovský, Assoc. prof., Ing., PhD., Milan Lacko, Assoc. prof., Ing., PhD., Martin Fabián, RNDr., PhD., Peter Slovenský, Ing., PhD., Peter Horňak, Assoc. prof., Dr., Miloš Matvija, Ing., PhD., Radka Gorejová, RNDr., PhD.

    GREEN TECHNOLOGIES

    ADVANCED MATERIALS AND PROCESSING ROUTES FOR PRODUCTION, DISTRIBUTION AND STORAGE OF HYDROGEN:

    Hydrogen is a key renewable vector undergoing considerable attention of scientific, business, policy in the world-leading economies. Europe as a region has unique assets that position the EU to pole position together with Japan, Korea, US and China. Slovakia and particularly Košice and the Košice Self-governing Region (KSK) are aware of the importance of hydrogen and hydrogen technologies and would like to further explore the implications of greater public and private investment in hydrogen as an alternative source of energy, particularly its spill-over effects on regional innovation, education, entrepreneurship and employment. The Centre is in this area focused on the development of advanced materials and technologies for new, more efficient methods of hydrogen production, safe storage with high energy density and optimization of materials and technologies for transportation of hydrogen in power distribution systems. Non-destructive corrosion monitoring of gas infrastructure potentially used for the fast transport of hydrogen on the site of interest and safety tasks join with diffusion control of hydrogen in metallic structures is investigating, too. Intensive development of fuel cells, where pure hydrogen is needed, stimulates electrolysers development for the future application in hydrogen energy and technology. From the point of view of possible ways of hydrogen production, one of the most prospective ones is the electrolysis of water, so our research activities will include the splitting of water by water-electrolysis, photo-electrolysis, photo-biological production and high-temperature decomposition.

    INTERNATIONAL COOPERATION OF CHT:

    The partnerships of the CHT teams with such organisations as INC – Institut für Nichtklassische Chemie e.V., Leipzig, Germany, Deutsches Elektronen-Synchrotron DESY, Hamburg, Germany, HYCENTA RESEARCH GMBH, TU Graz, Austria, Research cooperation with CVUT Prague, VUT Brno, VŠB TU Ostrava creates an extremely strong potential for further improving the quality of basic research and the application of the results to high-tech industry.

    MEMBERSHIP IN INTERNATIONAL NETWORKS:

    Member of the National Hydrogen Association, which is a member of Hydrogen Europe.

    KEY PERSONALITIES:

    Tomáš Brestovič, prof. Ing., PhD., Vladimír Zeleňák, prof. RNDr., DrSc.

    QUANTUM AND INFORMATION TECHNOLOGIES

    CQIT is based on two groups of specialists – physicists and IT scientists.

    The group of physicists at CQIT are recruited from the pool of a very unique experimental research complex in Slovakia – the Centre of Low Temperature Physics (CLTP) Košice, common laboratory of the Institute of Experimental Physics, Slovak Academy of Sciences and P. J. Šafárik University in Košice with more than 50-year tradition in cryogenics, vacuum technology, nanotechnology and frontier research of condensed matter down to ultralow temperatures. It is one of a dozen world laboratories capable of making measurements in microkelvin temperature range and extreme conditions of very high and very low magnetic fields, ultrahigh pressures and on a nanoscale. Ultra low-temperature framework enables a significant base in the strategically important areas of nanoscience, quantum technology and quantum materials. These areas act as key drivers for the development of scientific instrumentation, quantum-level technology and mensuration, generating new markets for the innovations which we anticipate will be the key outputs of CQIT and its commercial partners.

    IT scientists at CQIT are coming from the Faculty of Science of P.J. Šafárik University in Košice and the Faculty of elec¬tronics and informatics, Technical University of Košice. Both institutions have already cooperated in various scientific and infrastructure projects that resulted in the creation of the University Science Park Technicom https://www.uvptech¬nicom.sk/en/about-us/. The Technical University of Košice and Pavol Jozef Šafárik University in Košice are founding members of Košice IT Valley cluster and have intensive collaboration with IT industry in the area of applied research, education and training. Both institutions have a long-term background in the area of SW development, information system development, data science and artificial intelligence and cybersecurity. The team members from P.J. Šafárik University in Košice have quite a strong background in the area of Mathematics and Theoretical Computer Science while the team members from the Technical University possess knowledge and experience in the area of applied research. The synergic combination of both approaches creates a potential for the transfer of the results of research to practice. Košice IT cluster with more than 50 members provides a wide range of potential customers.

    CQIT focuses on the development and application of cyber or information security. Cybersecurity is one of the major challenges in the contemporary world and its failure at sensitive points can have a devastating consequence comparable to a world pandemic. CQTI will focus on classical approaches, quantum-safe encryption as well as postquantum cryptography. Technical University has a long-term tradition in network research, and it runs CISCO Academy. P.J. Šafárik University in Košice as the first Slovak university has an international registered CSIRT unit and it applies for accreditation. P.J. Šafárik University in Košice is a member QWorld community and through the QUTE.sk association realizes an activity within Quantum Flagship Initiative.

    The development of new and easy control means of interfaces in computers and generally in IT is another goal. The big demand for Big Data processing and consequent Data Analysis resulted in a building of corresponding competencies in both participating institutions. Modern Data Science is closely related to Artificial intelligence, particularly the exploration of machine learning techniques and (deep) neural networks.

    FOCUS OF RESEARCH:

    1. Cybersecurity and development of quantum communication grid in Slovakia
    2. Communication and collaboration systems
    3. Data Science and Artificial intelligence
    4. Quantum materials and quantum devices. Quantum enabling technologies at ultra-low temperatures
      1. Development and construction of new parametric amplifiers and microwave photon detectors
      2. Implementation of quantum bits
      3. Enabling quantum technologies

    INTERNATIONAL COOPERATION OF CQIT:

    In the area of computational and cognitive neuroscience, CQIT has developed collaborative work with prestigious international institutions: the Austrian Academy of Science (Austria), Boston University (USA), the University of California, Riverside (USA), National Center for Rehabilitative Auditory Research, Portland (USA) and OHSU, Martinos Center, Massachusetts General Hospital/Harvard Medical School (USA). As a particular example of successful collaboration, let us point out the collaboration with the California Institute of Technology on the development of a communication system that has transformed into a successful start-up eZuce. CQIT cooperates also with global companies, e.g. T-Systems (Germany), FPT Slovakia, Global Logic (USA), Ness, national and international security entities, e.g. Shadowserver, National security agency, and Governmental security team in the Slovak Republic.

    Within the EMP CQIT collaborates with six major industrial companies on new technologies and devices. These are Magnicon GmbH, Hamburg, Germany, Leiden Cryogenics B.V., The Netherlands, Cryoconcept France, Basel Precision Instruments GmbH, Oxford Instruments, and Bluefors Cryogenics Oy, Finland. Moreover, the technology partners and national standard laboratories – VTT Technical Research Centre of Finland, and The Physikalisch-Technische Bundesanstalt (PTB), Braunschweig and Berlin provide expertise and supervision.

    MEMBERSHIP IN INTERNATIONAL NETWORKS:

    CLTP is the founding member of the European Microkelvin Platform (EMP), established in 2014. Since )January 1, 2019, the EMP has been implementing a ma¬jor H2020 project from the Pillar of Excellent Science – Research infrastructure developing European research infrastructure for 2020 and beyond, fostering their innovation potential and human capital, and complementing this with the related Union policy and international cooperation. The consortium will stimulate further integration of ultralow temperature research in Europe through the development of new ideas, technology, applications and commercial exploitation. CQIT will directly exploit particular activities resulting from the EMP H2020 project oriented on prac¬tically applicable tasks and deliverables with major commerciali¬zation potential in the field of quantum technologies and quantum materials.

    Our group is a member of the Slovak National Research Platform on Quantum Technologies, a consortium of 4 research institutes of the Slovak Academy of Sciences (Institute of Physics, Institute of Experimental Physics, Institute of Electrical Engineering and Institute of Mathematics), Comenius University in Bratislava, Slovak University of Technol¬ogy in Bratislava and P. J. Šafárik University in Košice. The Quantum plan for Slovakia, declared by this consortium and supported by the Ministry of Education, Science, Research and Sport, is fully in accordance with the Quantum Technology Flagship, the one billion Euro initiative of the EU launched on November 1, 2019, with four strategic technol¬ogy goals: quantum computer, quantum communication grid, quantum sensors and metrology and quantum simulator, all coming from the frontier fundamental research aiming at quantum engineering, quantum software and systematic educa¬tion of the new generation of quantum physicists and engineers capable of realization of technology transfer to industrial application. The manifesto of QUIT.sk “FUTURE IS QUANTUM” describes the recent advancement of quantum technologies based on the so-called second quantum revolution related to exploitation of the phenomena as quantum interference, non-locality and entanglement which will soon bring progress in medical diagnostics, new materials and green energy, metrology and navigation, Artificial Intelligence, safe communication and internet.

    Pavol Jozef Šafárik University in Košice and Slovak Academy of Science are members of QWorld – a global network collaborating on education and implementation of quantum technologies and research activities. CSIRT-UPJS is an accredited member of the international organization of security teams – TF-CSIRT, and member of Honeynet.org and ISACA.

    KEY PERSONALITIES:

    Gabriel Semanišin, Prof., RNDr., PhD., Viliam Geffert, Prof., RNDr., DrSc., Jaroslav Porubän, Assoc. Prof., Ing., PhD., Peter Sinčák, Prof. Ing., PhD., Ján Paralič, Prof. Ing., PhD., Jozef Juhár, Prof., Ing., PhD., Peter Samuely, Prof. RNDr., DrSc., Peter Skyba, RNDr., DrSc., Erik Čižmár, Assoc. Prof. RNDr., PhD., Vladimír Komanický, PhD.